ODCs

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1 OMIM reference -
5 associated genes
5 signs/symptoms

PROTEIN INTERACTIONS: 2
COMMON SIGNS: 2

1 associated gene
6 signs/symptoms

Generalized junctional epidermolysis bullosa, non-Herlitz type

Acral dystrophic epidermolysis bullosa


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	LAMB3 LAMC2	(0.76) (0.76)	COL7A1 COL7A1

Citations in the biomedical literature:

Generalized junctional epidermolysis bullosa, non-Herlitz type		Acral dystrophic epidermolysis bullosa
	Synonym(s): - GABEB - Generalized atrophic benign epidermolysis bullosa - JEB-nH gen - Junctional epidermolysis bullosa generalisata mitis - Junctional epidermolysis bullosa, Disentis type		Synonym(s): - DEB, acral - DEB-ac

	Classification (Orphanet): - Rare developmental defect during embryogenesis - Rare genetic disease - Rare odontologic disease - Rare skin disease		Classification (Orphanet): - Rare genetic disease - Rare skin disease

	Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -		Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -

	Epidemiological data: Class of prevalence: unknown Average age onset: neonatal/infancy Average age of death: any age Type of inheritance: autosomal recessive		Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: neonatal/infancy Average age of death: - Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - No MeSH references		External references: No OMIM references No MeSH references


COMMON SIGNS	- Nails anomalies - Vesicles / bullous / exsudative lesions / bullous / cutaneous / mucosal detachment

Generalized junctional epidermolysis bullosa, non-Herlitz type		Acral dystrophic epidermolysis bullosa
	Frequent - Abnormal fingernails - Abnormal toenails Occasional - Anomalies of teeth and dentition		Very frequent - Autosomal dominant inheritance - Autosomal recessive inheritance - Follicular / erythematous / edematous papules / milium - Skin hypoplasia / aplasia / atrophy